The UK Structural & Biophysical Sciences group is a multi-disciplinary department within GSK R & D that provides molecular insights into drug discovery for both small molecule and biopharmaceutical programs.
We are currently expanding our CryoEM capability and have an exciting opportunity for a laboratory-based scientist with expertise in state-of-the-art electron microscopy techniques to join our group.A detailed knowledge of the sample preparation and optimisation processes required for high resolution single particle protein reconstructed structures is expected.An interest in other EM applications (MED, tomography) or exposure to crystallography and complementary biophysical methods such as SPR and mass spectrometry would be welcomed.
You will be responsible for supporting program teams and contributing to the wider protein structural and biophysical area. Eager to identify and drive forward improvements and innovations that advance drug discovery projects, the individual must be a collaborative team player able to work successfully with other scientists within the department and within diverse teams. You will be good at multi-tasking and capable of good experimental record-keeping, with excellent written and oral communication skills. An ability to work towards agreed timelines and effectively organise work will be considered a key asset of the successful applicant.
CLOSING DATE for applications: 13th October
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Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the cover letter of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
– A background in a biological, biochemical or physical sciences discipline, PhD level or equivalent
– Extensive experience of single-particle electron microscopy: sample preparation, data collection and processing.
– Demonstrated ability to design, perform and execute scientific strategy to success across multiple projects.
– Track record of innovation to solve challenging problems.
– Strong interpersonal, communication and team working skills.
– Excellent organisation skills.
– Thorough knowledge of protein analytical and biophysical characterisation techniques
– Strong protein biochemistry skills, including purification of protein complexes and membrane proteins
– Experience of scientific leadership to influence programs of research.
– Evidence of ability to coordinate projects with interconnecting activities.
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